Anti-FCN1 antibody (STJ192065)

SKU:
STJ192065
£48.00 - £252.00
Processing The item has been added

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Ficolin-1 is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FCN1
Gene ID: 2219
Uniprot ID: FCN1_HUMAN
Specificity: FCN1 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Function Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.
Protein Name Ficolin-1
Collagen/Fibrinogen Domain-Containing Protein 1
Ficolin-A
Ficolin-Alpha
M-Ficolin
Database Links Reactome: R-HSA-166662
Reactome: R-HSA-166663
Reactome: R-HSA-2855086
Reactome: R-HSA-6798695
Cellular Localisation Secreted
Cell Membrane
Peripheral Membrane Protein
Extracellular Side
Found On The Monocyte And Granulocyte Surface
Alternative Antibody Names Anti-Ficolin-1 antibody
Anti-Collagen/Fibrinogen Domain-Containing Protein 1 antibody
Anti-Ficolin-A antibody
Anti-Ficolin-Alpha antibody
Anti-M-Ficolin antibody
Anti-FCN1 antibody
Anti-FCNM antibody

Information sourced from Uniprot.org