Western blot analysis of extracts of various cell lines, using FCGR2C antibody (STJ112102) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-FCGR2C antibody (43-223) (STJ112102)

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STJ112102
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:1000-1:4000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FCGR2C
Gene ID: 9103
Uniprot ID: FCG2C_HUMAN
Immunogen Region: 43-223
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 43-223 of human FCGR2C (NP_963857.3).
Immunogen Sequence: TPAAPPKAVLKLEPQWINVL QEDSVTLTCRGTHSPESDSI PWFHNGNLIPTHTQPSYRFK ANNNDSGEYTCQTGQTSLSD PVHLTVLSEWLVLQTPHLEF QEGETIVLRCHSWKDKPLVK VTFFQNGKSKKFSRSDPNFS IPQANHSHSGDYHCTGNIGY TLYSSKPVTITVQAPSSSPM G
Tissue Specificity Isoform IIC1 is detected in monocytes, macrophages, polymorphonuclear cells and natural killer cells.
Post Translational Modifications Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN and SYK.
Function Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.
Protein Name Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-C
Igg Fc Receptor Ii-C
Cdw32
Fc-Gamma Rii-C
Fc-Gamma-Riic
Fcrii-C
Cd Antigen Cd32
Cellular Localisation Isoform Iic4: Cytoplasm
Isoform Iic3: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform Iic2: Cell Membrane
Isoform Iic1: Cell Membrane
Alternative Antibody Names Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-C antibody
Anti-Igg Fc Receptor Ii-C antibody
Anti-Cdw32 antibody
Anti-Fc-Gamma Rii-C antibody
Anti-Fc-Gamma-Riic antibody
Anti-Fcrii-C antibody
Anti-Cd Antigen Cd32 antibody
Anti-FCGR2C antibody
Anti-CD32 antibody
Anti-FCG2 antibody
Anti-IGFR2 antibody

Information sourced from Uniprot.org

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