| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FCGR2C |
| Gene ID: |
9103 |
| Uniprot ID: |
FCG2C_HUMAN |
| Immunogen Region: |
43-223 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 43-223 of human FCGR2C (NP_963857.3). |
| Immunogen Sequence: |
TPAAPPKAVLKLEPQWINVL QEDSVTLTCRGTHSPESDSI PWFHNGNLIPTHTQPSYRFK ANNNDSGEYTCQTGQTSLSD PVHLTVLSEWLVLQTPHLEF QEGETIVLRCHSWKDKPLVK VTFFQNGKSKKFSRSDPNFS IPQANHSHSGDYHCTGNIGY TLYSSKPVTITVQAPSSSPM G |
| Tissue Specificity | Isoform IIC1 is detected in monocytes, macrophages, polymorphonuclear cells and natural killer cells. |
| Post Translational Modifications | Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN and SYK. |
| Function | Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. |
| Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-CIgg Fc Receptor Ii-CCdw32Fc-Gamma Rii-CFc-Gamma-RiicFcrii-CCd Antigen Cd32 |
| Cellular Localisation | Isoform Iic4: CytoplasmIsoform Iic3: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Iic2: Cell MembraneIsoform Iic1: Cell Membrane |
| Alternative Antibody Names | Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-C antibodyAnti-Igg Fc Receptor Ii-C antibodyAnti-Cdw32 antibodyAnti-Fc-Gamma Rii-C antibodyAnti-Fc-Gamma-Riic antibodyAnti-Fcrii-C antibodyAnti-Cd Antigen Cd32 antibodyAnti-FCGR2C antibodyAnti-CD32 antibodyAnti-FCG2 antibodyAnti-IGFR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
