IHC staining of Human tonsil tissue paraffin-embedded, diluted at 1:200.

Anti-FCER2 antibody [1E9] (STJ96951)

SKU:
STJ96951
£48.00 - £252.00
Processing The item has been added

Host: Mouse
Applications: IF/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-Low affinity immunoglobulin epsilon Fc receptor is suitable for use in Immunofluorescence and Immunohistochemistry research applications.
Clonality : Monoclonal
Clone ID : 1E9
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: IF 1:50-200
IHC 1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FCER2
Gene ID: 2208
Uniprot ID: FCER2_HUMAN
Specificity: The antibody detects endogenous CD23 proteins.
Immunogen: Synthetic Peptide of CD23
Post Translational Modifications N- and O-glycosylated. The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding.
Function Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway.
Protein Name Low Affinity Immunoglobulin Epsilon Fc Receptor
Blast-2
C-Type Lectin Domain Family 4 Member J
Fc-Epsilon-Rii
Immunoglobulin E-Binding Factor
Lymphocyte Ige Receptor
Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form
Database Links Reactome: R-HSA-2197563
Reactome: R-HSA-6783783
Reactome: R-HSA-6785807
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Lipid-Anchor
Secreted
Also Exists As A Soluble Excreted Form
Scd23
Alternative Antibody Names Anti-Low Affinity Immunoglobulin Epsilon Fc Receptor antibody
Anti-Blast-2 antibody
Anti-C-Type Lectin Domain Family 4 Member J antibody
Anti-Fc-Epsilon-Rii antibody
Anti-Immunoglobulin E-Binding Factor antibody
Anti-Lymphocyte Ige Receptor antibody
Anti-Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form antibody
Anti-FCER2 antibody
Anti-CD23A antibody
Anti-CLEC4J antibody
Anti-FCE2 antibody
Anti-IGEBF antibody

Information sourced from Uniprot.org