| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-EXTL2 (41-330) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
EXTL2 |
| Gene ID: |
2135 |
| Uniprot ID: |
EXTL2_HUMAN |
| Immunogen Region: |
41-330 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 41-330 of human EXTL2 (NP_001430.1). |
| Immunogen Sequence: |
PSVKEDKMLMLRREIKSQGK STMDSFTLIMQTYNRTDLLL KLLNHYQAVPNLHKVIVVWN NIGEKAPDELWNSLGPHPIP VIFKQQTANRMRNRLQVFPE LETNAVLMVDDDTLISTPDL VFAFSVWQQFPDQIVGFVPR KHVSTSSGIYSYGSFEMQAP GSGNGDQYSMVLIGASFFNS KYLELFQRQPAAVHALIDDT QNCDDIAMNFIIAKHIGKTS GIFVKPVNMDNLEKETNSG |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
| Function | Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. |
| Protein Name | Exostosin-Like 2Alpha-1 -4-N-Acetylhexosaminyltransferase Extl2Alpha-Galnact Extl2Ext-Related Protein 2Glucuronyl-Galactosyl-Proteoglycan 4-Alpha-N-Acetylglucosaminyltransferase Cleaved Into - Processed Exostosin-Like 2 |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinProcessed Exostosin-Like 2: SecretedA Soluble Form Is Found In The Serum |
| Alternative Antibody Names | Anti-Exostosin-Like 2 antibodyAnti-Alpha-1 -4-N-Acetylhexosaminyltransferase Extl2 antibodyAnti-Alpha-Galnact Extl2 antibodyAnti-Ext-Related Protein 2 antibodyAnti-Glucuronyl-Galactosyl-Proteoglycan 4-Alpha-N-Acetylglucosaminyltransferase Cleaved Into - Processed Exostosin-Like 2 antibodyAnti-EXTL2 antibodyAnti-EXTR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
