| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ENPP6 (91-440) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ENPP6 |
| Gene ID: |
133121 |
| Uniprot ID: |
ENPP6_HUMAN |
| Immunogen Region: |
91-440 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 91-440 of human ENPP6 (NP_699174.1). |
| Immunogen Sequence: |
GNYMWDPTTNKSFDIGVNKD SLMPLWWNGSEPLWVTLTKA KRKVYMYYWPGCEVEILGVR PTYCLEYKNVPTDINFANAV SDALDSFKSGRADLAAIYHE RIDVEGHHYGPASPQRKDAL KAVDTVLKYMTKWIQERGLQ DRLNVIIFSDHGMTDIFWMD KVIELNKYISLNDLQQVKDR GPVVSLWPAPGKHSEIYNKL STVEHMTVYEKEAIPSRFYY KKGKFVSPLTLVADEGWFI |
| Tissue Specificity | Predominantly expressed in kidney and brain. In the kidney, expressed specifically in the proximal tubules and thin descending limbs of Henle (at protein level). |
| Function | Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids. |
| Protein Name | Glycerophosphocholine Cholinephosphodiesterase Enpp6Gpc-CpdeCholine-Specific Glycerophosphodiester PhosphodiesteraseEctonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6E-Npp 6Npp-6 |
| Database Links | Reactome: R-HSA-6814848 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorA Small Amount Of The Protein May Be Found In The Extracellular Milieu |
| Alternative Antibody Names | Anti-Glycerophosphocholine Cholinephosphodiesterase Enpp6 antibodyAnti-Gpc-Cpde antibodyAnti-Choline-Specific Glycerophosphodiester Phosphodiesterase antibodyAnti-Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 antibodyAnti-E-Npp 6 antibodyAnti-Npp-6 antibodyAnti-ENPP6 antibodyAnti-UNQ1889 antibodyAnti-PRO4334 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
