Function | Transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation. May act as a repressor for a specific subset of ETS/AP-1-responsive genes and as a modulator of the nuclear response to mitogen-activated protein kinase signaling cascades. Binds to DNA sequences containing the consensus nucleotide core sequence GGAA. Involved in regulation of TNFRSF10B/DR5 expression through Ets-binding sequences on the TNFRSF10B/DR5 promoter. May contribute to development and carcinogenesis by acting as a tumor suppressor gene or anti-oncogene. |
Protein Name | Ets Homologous FactorHehfEts Domain-Containing Transcription FactorEpithelium-Specific Ets Transcription Factor 3Ese-3 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Ets Homologous Factor antibodyAnti-Hehf antibodyAnti-Ets Domain-Containing Transcription Factor antibodyAnti-Epithelium-Specific Ets Transcription Factor 3 antibodyAnti-Ese-3 antibodyAnti-EHF antibodyAnti-ESE3 antibodyAnti-ESE3B antibodyAnti-ESEJ antibody |
Information sourced from Uniprot.org