| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DYNLT3 |
| Gene ID: | 6990 |
| Uniprot ID: | DYLT3_HUMAN |
| Immunogen Region: | 9-99 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 9-99 of human DYNLT3 (NP_006511.1). |
| Immunogen Sequence: | DEVGFNAEEAHNIVKECVDG VLGGEDYNHNNINQWTASIV EQSLTHLVKLGKAYKYIVTC AVVQKSAYGFHTASSCFWDT TSDGTCTVRWE |
| Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis. |
| Protein Name | Dynein Light Chain Tctex-Type 3Protein 91/23T-Complex-Associated Testis-Expressed 1-Like |
| Cellular Localisation | NucleusCytoplasmCytoskeletonChromosomeCentromereKinetochoreColocalizes With Bub3 At Kinetochores Specifically During Prometaphase |
| Alternative Antibody Names | Anti-Dynein Light Chain Tctex-Type 3 antibodyAnti-Protein 91/23 antibodyAnti-T-Complex-Associated Testis-Expressed 1-Like antibodyAnti-DYNLT3 antibodyAnti-TCTE1L antibodyAnti-TCTE1XL antibody |
Information sourced from Uniprot.org