| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DUSP3 |
| Gene ID: | 1845 |
| Uniprot ID: | DUS3_HUMAN |
| Immunogen Region: | 1-185 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human DUSP3 (NP_004081.1). |
| Immunogen Sequence: | MSGSFELSVQDLNDLLSDGS GCYSLPSQPCNEVTPRIYVG NASVAQDIPKLQKLGITHVL NAAEGRSFMHVNTNANFYKD SGITYLGIKANDTQEFNLSA YFERAADFIDQALAQKNGRV LVHCREGYSRSPTLVIAYLM MRQKMDVKSALSIVRQNREI GPNDGFLAQLCQLNDRLAKE GKLKP |
| Function | Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2. |
| Protein Name | Dual Specificity Protein Phosphatase 3Dual Specificity Protein Phosphatase VhrVaccinia H1-Related PhosphataseVhr |
| Database Links | Reactome: R-HSA-202670 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonFlagellum Axoneme |
| Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 3 antibodyAnti-Dual Specificity Protein Phosphatase Vhr antibodyAnti-Vaccinia H1-Related Phosphatase antibodyAnti-Vhr antibodyAnti-DUSP3 antibodyAnti-VHR antibody |
Information sourced from Uniprot.org