| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DNTTIP1 (1-329) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DNTTIP1 |
| Gene ID: |
116092 |
| Uniprot ID: |
TDIF1_HUMAN |
| Immunogen Region: |
1-329 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-329 of human DNTTIP1 (NP_443183.1). |
| Immunogen Sequence: |
MGATGDAEQPRGPSGAERGG LELGDAGAAGQLVLTNPWNI MIKHRQVQRRGRRSQMTTSF TDPAISMDLLRAVLQPSINE EIQTVFNKYMKFFQKAALNV RDNVGEEVDAEQLIQEACRS CLEQAKLLFSDGEKVIPRLT HELPGIKRGRQAEEECAHRG SPLPKKRKGRPPGHILSSDR AAAGMVWKPKSCEPIRREGP KWDPARLNESTTFVLGSRAN KALGMGGTRGRIYIKHPHL |
| Function | Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes.may recruit HDAC1 complexes to nucleosomes or naked DNA. |
| Protein Name | Deoxynucleotidyltransferase Terminal-Interacting Protein 1Terminal Deoxynucleotidyltransferase-Interacting Factor 1Tdif1Tdt-Interacting Factor 1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Deoxynucleotidyltransferase Terminal-Interacting Protein 1 antibodyAnti-Terminal Deoxynucleotidyltransferase-Interacting Factor 1 antibodyAnti-Tdif1 antibodyAnti-Tdt-Interacting Factor 1 antibodyAnti-DNTTIP1 antibodyAnti-C20orf167 antibodyAnti-TDIF1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and CRYZ knockout (KO) HeLa cells, using [KO Validated] CRYZ Rabbit polyclonal antibody (STJ11100873) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89807/358274/STJ11100873_1__03594.1713122620.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CRYZ knockout (KO) HeLa cells, using [KO Validated] CRYZ Rabbit polyclonal antibody (STJ11100873) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.")
