| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DNTTIP1 |
| Gene ID: | 116092 |
| Uniprot ID: | TDIF1_HUMAN |
| Immunogen Region: | 1-329 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-329 of human DNTTIP1 (NP_443183.1). |
| Immunogen Sequence: | MGATGDAEQPRGPSGAERGG LELGDAGAAGQLVLTNPWNI MIKHRQVQRRGRRSQMTTSF TDPAISMDLLRAVLQPSINE EIQTVFNKYMKFFQKAALNV RDNVGEEVDAEQLIQEACRS CLEQAKLLFSDGEKVIPRLT HELPGIKRGRQAEEECAHRG SPLPKKRKGRPPGHILSSDR AAAGMVWKPKSCEPIRREGP KWDPARLNESTTFVLGSRAN KALGMGGTRGRIYIKHPHL |
| Function | Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes.may recruit HDAC1 complexes to nucleosomes or naked DNA. |
| Protein Name | Deoxynucleotidyltransferase Terminal-Interacting Protein 1Terminal Deoxynucleotidyltransferase-Interacting Factor 1Tdif1Tdt-Interacting Factor 1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Deoxynucleotidyltransferase Terminal-Interacting Protein 1 antibodyAnti-Terminal Deoxynucleotidyltransferase-Interacting Factor 1 antibodyAnti-Tdif1 antibodyAnti-Tdt-Interacting Factor 1 antibodyAnti-DNTTIP1 antibodyAnti-C20orf167 antibodyAnti-TDIF1 antibody |
Information sourced from Uniprot.org