| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DND1 (1-140) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DND1 |
| Gene ID: |
373863 |
| Uniprot ID: |
DND1_HUMAN |
| Immunogen Region: |
1-140 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human DND1 (NP_919225.1). |
| Immunogen Sequence: |
MQSKRDCELWCERVNPENKA ALEAWVRETGIRLVQVNGQR KYGGPPPGWVGSPPPAGSEV FIGRLPQDVYEHQLIPLFQR VGRLYEFRLMMTFSGLNRGF AYARYSSRRGAQAAIATLHN HPLRPSCPLLVCRSTEKCEL |
| Function | RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells. Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival. However, does not seem to be essential for PGC migration. |
| Protein Name | Dead End Protein Homolog 1Rna-Binding Motif - Single-Stranded-Interacting Protein 4 |
| Cellular Localisation | NucleusCytoplasmPerinuclear Germ GranulesAlso Called Germ Plasm Or Chromatoid BodyColocalizes In Perinuclear Sites With Apobec3 |
| Alternative Antibody Names | Anti-Dead End Protein Homolog 1 antibodyAnti-Rna-Binding Motif - Single-Stranded-Interacting Protein 4 antibodyAnti-DND1 antibodyAnti-RBMS4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
