| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DNAH5 |
| Gene ID: | 1767 |
| Uniprot ID: | DYH5_HUMAN |
| Immunogen Region: | 400-650 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-650 of human DNAH5 (NP_001360.1). |
| Immunogen Sequence: | VTNQIISACKAYITNNGTAS IWNQPQDVVEEKILSAIKLK QEYQLCFHKTKQKLKQNPNA KQFDFSEMYIFGKFETFHRR LAKIIDIFTTLKTYSVLQDS TIEGLEDMATKYQGIVATIK KKEYNFLDQRKMDFDQDYEE FCKQTNDLHNELRKFMDVTF AKIQNTNQALRMLKKFERLN IPNLGIDDKYQLILENYGAD IDMISKLYTKQKYDPPLARN QPPIAGKILWARQLFHRIQ |
| Tissue Specificity | Expressed in airway epithelial cells (at protein level). Not detected in spermatozoa (at protein level). |
| Function | Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity.the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles. |
| Protein Name | Dynein Axonemal Heavy Chain 5Axonemal Beta Dynein Heavy Chain 5Ciliary Dynein Heavy Chain 5 |
| Cellular Localisation | CytoplasmCytoskeletonCilium Axoneme |
| Alternative Antibody Names | Anti-Dynein Axonemal Heavy Chain 5 antibodyAnti-Axonemal Beta Dynein Heavy Chain 5 antibodyAnti-Ciliary Dynein Heavy Chain 5 antibodyAnti-DNAH5 antibodyAnti-DNAHC5 antibodyAnti-HL1 antibodyAnti-KIAA1603 antibody |
Information sourced from Uniprot.org