Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-DNAH5 (400-650) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
DNAH5 |
Gene ID: |
1767 |
Uniprot ID: |
DYH5_HUMAN |
Immunogen Region: |
400-650 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 400-650 of human DNAH5 (NP_001360.1). |
Immunogen Sequence: |
VTNQIISACKAYITNNGTAS IWNQPQDVVEEKILSAIKLK QEYQLCFHKTKQKLKQNPNA KQFDFSEMYIFGKFETFHRR LAKIIDIFTTLKTYSVLQDS TIEGLEDMATKYQGIVATIK KKEYNFLDQRKMDFDQDYEE FCKQTNDLHNELRKFMDVTF AKIQNTNQALRMLKKFERLN IPNLGIDDKYQLILENYGAD IDMISKLYTKQKYDPPLARN QPPIAGKILWARQLFHRIQ |
Tissue Specificity | Expressed in airway epithelial cells (at protein level). Not detected in spermatozoa (at protein level). |
Function | Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity.the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles. |
Protein Name | Dynein Axonemal Heavy Chain 5Axonemal Beta Dynein Heavy Chain 5Ciliary Dynein Heavy Chain 5 |
Cellular Localisation | CytoplasmCytoskeletonCilium Axoneme |
Alternative Antibody Names | Anti-Dynein Axonemal Heavy Chain 5 antibodyAnti-Axonemal Beta Dynein Heavy Chain 5 antibodyAnti-Ciliary Dynein Heavy Chain 5 antibodyAnti-DNAH5 antibodyAnti-DNAHC5 antibodyAnti-HL1 antibodyAnti-KIAA1603 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance