| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DNAAF1 |
| Gene ID: | 123872 |
| Uniprot ID: | DAAF1_HUMAN |
| Immunogen Region: | 516-725 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 516-725 of human DNAAF1 (NP_848547.4). |
| Immunogen Sequence: | VATEGVFVTELDGTRTEDLE TIRLETKETFCIDDLPDLED DDETGKSLEDQNMCFPKIEV ISSLSDDSDPELDYTSLPVL ENLPTDTLSNIFAVSKDTSK AARVPFTDIFKKEAKRDLEI RKQDTKSPRPLIQELSDEDP SGQLLMPPTCQRDAAPLTSS GDRDSDFLAASSPVPTESAA TPPETCVGVAQPSQALPTWD LTAFPAPKAS |
| Tissue Specificity | Mainly expressed in trachea and testis. |
| Function | Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli. |
| Protein Name | Dynein Axonemal Assembly Factor 1Leucine-Rich Repeat-Containing Protein 50 |
| Cellular Localisation | Cell ProjectionCiliumCytoplasmCytoskeletonSpindle PoleIn Hek293t CellsIt Is Diffusely Cytoplasmic And Concentrates At The Mitotic Spindle PolesWhile In Mdck CellsIt Localizes In The CiliumIn VivoThis Protein Is Probably Restricted To The Cilium |
| Alternative Antibody Names | Anti-Dynein Axonemal Assembly Factor 1 antibodyAnti-Leucine-Rich Repeat-Containing Protein 50 antibodyAnti-DNAAF1 antibodyAnti-LRRC50 antibody |
Information sourced from Uniprot.org