Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-DET1 homolog (48-98 aa) is suitable for use in Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DET1 |
Gene ID: | 55070 |
Uniprot ID: | DET1_HUMAN |
Immunogen Region: | 48-98 aa |
Specificity: | This antibody detects endogenous levels of DET1 at Human/Mouse |
Immunogen: | Synthesized peptide derived from the human DET1 at the amino acid range 48-98 |
Function | Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation. |
Protein Name | Det1 HomologDe-Etiolated-1 Homolog |
Database Links | Reactome: R-HSA-983168 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Det1 Homolog antibodyAnti-De-Etiolated-1 Homolog antibodyAnti-DET1 antibody |
Information sourced from Uniprot.org