| Tissue Specificity | Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis. |
| Function | Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules. |
| Protein Name | L-Xylulose ReductaseXrCarbonyl Reductase IiDicarbonyl/L-Xylulose ReductaseKidney Dicarbonyl ReductaseKidcrShort Chain Dehydrogenase/Reductase Family 20c Member 1Sperm Surface Protein P34h |
| Database Links | Reactome: R-HSA-5661270Reactome: R-HSA-5662853 |
| Cellular Localisation | MembranePeripheral Membrane ProteinProbably Recruited To Membranes Via An Interaction With Phosphatidylinositol |
| Alternative Antibody Names | Anti-L-Xylulose Reductase antibodyAnti-Xr antibodyAnti-Carbonyl Reductase Ii antibodyAnti-Dicarbonyl/L-Xylulose Reductase antibodyAnti-Kidney Dicarbonyl Reductase antibodyAnti-Kidcr antibodyAnti-Short Chain Dehydrogenase/Reductase Family 20c Member 1 antibodyAnti-Sperm Surface Protein P34h antibodyAnti-DCXR antibodyAnti-SDR20C1 antibody |
Information sourced from Uniprot.org
