| Tissue Specificity | Widely expressed, with highest levels in the heart, placenta, spleen, peripheral blood leukocytes and adrenal gland. In lung, expressed in the interstitial macrophages, and slightly in smooth muscle cells. |
| Function | Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4. |
| Protein Name | Cysteinyl Leukotriene Receptor 2Cysltr2G-Protein Coupled Receptor Gpcr21Hgpcr21G-Protein Coupled Receptor Hg57Hpn321 |
| Database Links | Reactome: R-HSA-391906Reactome: R-HSA-416476Reactome: R-HSA-418555Reactome: R-HSA-9664535 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cysteinyl Leukotriene Receptor 2 antibodyAnti-Cysltr2 antibodyAnti-G-Protein Coupled Receptor Gpcr21 antibodyAnti-Hgpcr21 antibodyAnti-G-Protein Coupled Receptor Hg57 antibodyAnti-Hpn321 antibodyAnti-CYSLTR2 antibodyAnti-CYSLT2 antibodyAnti-CYSLT2R antibodyAnti-PSEC0146 antibody |
Information sourced from Uniprot.org
