| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
Cyp4a14 |
| Gene ID: |
13119 |
| Uniprot ID: |
CP4AE_MOUSE |
| Specificity: |
A synthesized peptide derived from Mouse Cyp4a14 |
| Tissue Specificity | Gender- and strain-specific expression in kidney (at protein level). Predominantly expressed in females, the expression among strains decreasing in the following order: FVB/N > NMRI > Balb/c > 129 Sv/J > C57BL/6. Expressed at very low level in liver, kidney and spleen of both male and female C57BL/6 X CBA hybrid mice. |
| Function | A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR.NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of saturated carbon hydrogen bonds of fatty acids. May act as a major omega- and ommega-1 hydroxylase for dodecanoic (lauric) acid in kidney. Catalyzes with low efficiency the epoxidation of 11,12-double bond of arachidonic acid. |
| Protein Name | Cytochrome P450 4a14Cypiva14Lauric Acid Hydroxylase |
| Database Links | Reactome: R-MMU-211935Reactome: -MMU-211958Reactome: -MMU-211979Reactome: -MMU-2142691 |
| Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane ProteinMicrosome Membrane |
| Alternative Antibody Names | Anti-Cytochrome P450 4a14 antibodyAnti-Cypiva14 antibodyAnti-Lauric Acid Hydroxylase antibodyAnti-Cyp4a14 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
