• Western blot with Anti-CXCR2 Antibody (STJ500648) with peptide on at 1:500 dilution in buffer.

Anti-CXCR2 antibody (18-39) (STJ500648)

SKU:
STJ500648-100

£481.50
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Host: Rabbit
Applications: CM/ELISA/ICC/IF/IHC/IP/FC/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CXCR2 (18-39) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Flow Cytometry and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: ~0.50 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:250
IHC: 1:200
ICC: 1:200
IF: 1:200
CFM: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: CXCR2
Gene ID: 3579
Uniprot ID: CXCR2_HUMAN
Immunogen Region: 18-39
Immunogen: Synthetic peptide: EDLSNYSYSSTLPPFLLDAAPC Corresponding to amino acids 18-39 of Human CXCR2.
Post Translational Modifications Phosphorylated upon ligand binding.which is required for desensitization. (Microbial infection) Proteolytically cleaved by Staphylococcus aureus staphopain A/SspP. This cleavage inhibits CXCR2-dependent neutrophil activation and chemotaxis.
Function Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Protein Name C-X-C Chemokine Receptor Type 2
Cxc-R2
Cxcr-2
Cdw128b
Gro/Mgsa Receptor
High Affinity Interleukin-8 Receptor B
Il-8r B
Il-8 Receptor Type 2
Cd Antigen Cd182
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-C-X-C Chemokine Receptor Type 2 antibody
Anti-Cxc-R2 antibody
Anti-Cxcr-2 antibody
Anti-Cdw128b antibody
Anti-Gro/Mgsa Receptor antibody
Anti-High Affinity Interleukin-8 Receptor B antibody
Anti-Il-8r B antibody
Anti-Il-8 Receptor Type 2 antibody
Anti-Cd Antigen Cd182 antibody
Anti-CXCR2 antibody
Anti-IL8RB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance