Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Gene Symbol: |
CXCL3 |
Gene ID: |
2921 |
Uniprot ID: |
CXCL3_HUMAN |
Immunogen Region: |
1-107 aa |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-107 of human CXCL3 (NP_002081.2). |
Immunogen Sequence: |
MAHATLSAAPSNPRLLRVAL LLLLLVAASRRAAGASVVTE LRCQCLQTLQGIHLKNIQSV NVRSPGPHCAQTEVIATLKN GKKACLNPASPMVQKIIEKI LNKGSTN |
Post Translational Modifications | N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes. |
Function | Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. |
Protein Name | C-X-C Motif Chemokine 3Gro-Gamma(1-73Growth-Regulated Protein GammaGro-GammaMacrophage Inflammatory Protein 2-BetaMip2-Beta Cleaved Into - Gro-Gamma(5-73 |
Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-C-X-C Motif Chemokine 3 antibodyAnti-Gro-Gamma(1-73 antibodyAnti-Growth-Regulated Protein Gamma antibodyAnti-Gro-Gamma antibodyAnti-Macrophage Inflammatory Protein 2-Beta antibodyAnti-Mip2-Beta Cleaved Into - Gro-Gamma(5-73 antibodyAnti-CXCL3 antibodyAnti-GRO3 antibodyAnti-GROG antibodyAnti-SCYB3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance