| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CPSF4 (1-244) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CPSF4 |
| Gene ID: |
10898 |
| Uniprot ID: |
CPSF4_HUMAN |
| Immunogen Region: |
1-244 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human CPSF4 (NP_001075028.1). |
| Immunogen Sequence: |
MQEIIASVDHIKFDLEIAVE QQLGAQPLPFPGMDKSGAAV CEFFLKAACGKGGMCPFRHI SGEKTVVCKHWLRGLCKKGD QCEFLHEYDMTKMPECYFYS KFGECSNKECPFLHIDPESK IKDCPWYDRGFCKHGPLCRH RHTRRVICVNYLVGFCPEGP SCKFMHPRFELPMGTTEQPP LPQQTQPPAKQRTPQVIGVM QSQNSSAGNRGPRPLEQVTC YKCGEKGHYANRCTKGHLA |
| Function | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U). |
| Protein Name | Cleavage And Polyadenylation Specificity Factor Subunit 4Cleavage And Polyadenylation Specificity Factor 30 Kda SubunitCpsf 30 Kda SubunitNs1 Effector Domain-Binding Protein 1Neb-1No Arches Homolog |
| Database Links | Reactome: R-HSA-159231Reactome: R-HSA-168315Reactome: R-HSA-6784531Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856Reactome: R-HSA-77595 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cleavage And Polyadenylation Specificity Factor Subunit 4 antibodyAnti-Cleavage And Polyadenylation Specificity Factor 30 Kda Subunit antibodyAnti-Cpsf 30 Kda Subunit antibodyAnti-Ns1 Effector Domain-Binding Protein 1 antibodyAnti-Neb-1 antibodyAnti-No Arches Homolog antibodyAnti-CPSF4 antibodyAnti-CPSF30 antibodyAnti-NAR antibodyAnti-NEB1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and LRRC59 knockout (KO) 293T cells, using [KO Validated] LRRC59 Rabbit polyclonal antibody (STJ11102870) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/163813/364584/STJ11102870_1__80247.1713129696.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and LRRC59 knockout (KO) 293T cells, using [KO Validated] LRRC59 Rabbit polyclonal antibody (STJ11102870) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
