Tissue Specificity | Mainly detected in blood plasma. Abundant in placenta and kidney. Present at low level in muscles, liver and skin fibroblasts. Not detected in brain or white blood cells (at protein level). |
Post Translational Modifications | N-glycosylated. The secreted form is modified by hybrid or complex type oligosaccharide chains. |
Function | Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor. |
Protein Name | Carboxypeptidase QLysosomal DipeptidasePlasma Glutamate Carboxypeptidase |
Cellular Localisation | Endoplasmic ReticulumGolgi ApparatusLysosomeSecretedSecretion Is Stimulated By Tsh/Thyroid-Stimulating HormoneIns/Insulin And Sst/Somatostatin |
Alternative Antibody Names | Anti-Carboxypeptidase Q antibodyAnti-Lysosomal Dipeptidase antibodyAnti-Plasma Glutamate Carboxypeptidase antibodyAnti-CPQ antibodyAnti-LCH1 antibodyAnti-PGCP antibody |
Information sourced from Uniprot.org