| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CMA1 (81-247) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CMA1 |
| Gene ID: |
1215 |
| Uniprot ID: |
CMA1_HUMAN |
| Immunogen Region: |
81-247 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 81-247 of human Mast Cell Chymase (CMA1) (NP_001827.1). |
| Immunogen Sequence: |
ITEEEDTWQKLEVIKQFRHP KYNTSTLHHDIMLLKLKEKA SLTLAVGTLPFPSQFNFVPP GRMCRVAGWGRTGVLKPGSD TLQEVKLRLMDPQACSHFRD FDHNLQLCVGNPRKTKSAFK GDSGGPLLCAGVAQGIVSYG RSDAKPPAVFTRISHYRPWI NQILQAN |
| Tissue Specificity | Mast cells in lung, heart, skin and placenta. Expressed in both normal skin and in urticaria pigmentosa lesions. |
| Function | Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. |
| Protein Name | ChymaseAlpha-ChymaseMast Cell Protease I |
| Database Links | Reactome: R-HSA-1433557Reactome: R-HSA-1592389Reactome: R-HSA-2022377 |
| Cellular Localisation | SecretedCytoplasmic GranuleMast Cell Granules |
| Alternative Antibody Names | Anti-Chymase antibodyAnti-Alpha-Chymase antibodyAnti-Mast Cell Protease I antibodyAnti-CMA1 antibodyAnti-CYH antibodyAnti-CYM antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
