| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Chordin (905-954 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-200ELISA 1:10000-20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CHRD |
| Gene ID: | 8646 |
| Uniprot ID: | CHRD_HUMAN |
| Immunogen Region: | 905-954 aa |
| Specificity: | The antibody detects endogenous Chordin |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the C-terminal region of human CHRD at the amino acid range 905-954 |
| Post Translational Modifications | Cleaved by tolloid proteases.cleavage participates in dorsoventral patterning during early development. |
| Function | Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. |
| Protein Name | Chordin |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Chordin antibodyAnti-CHRD antibodyAnti-UNQ217 antibodyAnti-PRO243 antibody |
Information sourced from Uniprot.org
