| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | CEP57 |
| Gene ID: | 9702 |
| Uniprot ID: | CEP57_HUMAN |
| Immunogen Region: | 1-240 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CEP57 (NP_055494.2). |
| Immunogen Sequence: | MAAASVSAASGSHLSNSFAE PSRSNGSMVRHSSSPYVVYP SDKPFLNSDLRRSPSKPTLA YPESNSRAIFSALKNLQDKI RRLELERIQAEESVKTLSRE TIEYKKVLDEQIQERENSKN EESKHNQELTSQLLAAENKC NLLEKQLEYMRNMIKHAEME RTSVLEKQVSLERERQHDQT HVQSQLEKLDLLEQEYNKLT TMQALAEKKMQELEAKLHEE EQERKRMQAKAAELQTGLE |
| Tissue Specificity | Ubiquitous. |
| Function | Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1. |
| Protein Name | Centrosomal Protein Of 57 KdaCep57Fgf2-Interacting ProteinTestis-Specific Protein 57Translokin |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosome |
| Alternative Antibody Names | Anti-Centrosomal Protein Of 57 Kda antibodyAnti-Cep57 antibodyAnti-Fgf2-Interacting Protein antibodyAnti-Testis-Specific Protein 57 antibodyAnti-Translokin antibodyAnti-CEP57 antibodyAnti-KIAA0092 antibodyAnti-TSP57 antibody |
Information sourced from Uniprot.org
