| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CEP170 |
| Gene ID: | 9859 |
| Uniprot ID: | CE170_HUMAN |
| Immunogen Region: | 1505-1584 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1505-1584 of human CEP170 (NP_055627.2). |
| Immunogen Sequence: | NMGFPSAMLPSPPKQKSSPV NNHHSPGQTPTLGQPEARAL HPAAVSAAAEFENAESEADF SIHFNRFNPDGEEEDVTVQE |
| Post Translational Modifications | Phosphorylated.probably by PLK1. |
| Function | Plays a role in microtubule organization. Required for centriole subdistal appendage assembly. |
| Protein Name | Centrosomal Protein Of 170 Kda Cep170 Karp-1-Binding Protein Karp1-Binding Protein |
| Cellular Localisation | Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome Centriole Spindle Associated With The Mature Mother Centriole Associated With Spindle Microtubules During Mitosis Localizes To The Distal Appendage Region Of The Centriole Localizes At The Centriole Proximal Ends |
| Alternative Antibody Names | Anti-Centrosomal Protein Of 170 Kda antibody Anti-Cep170 antibody Anti-Karp-1-Binding Protein antibody Anti-Karp1-Binding Protein antibody Anti-CEP170 antibody Anti-FAM68A antibody Anti-KAB antibody Anti-KIAA0470 antibody |
Information sourced from Uniprot.org