| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CEACAM4 |
| Gene ID: | 1089 |
| Uniprot ID: | CEAM4_HUMAN |
| Immunogen Region: | 36-155 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 36-155 of human CEACAM4 (NP_001808.2). |
| Immunogen Sequence: | FTIEALPSSAAEGKDVLLLA CNISETIQAYYWHKGKTAEG SPLIAGYITDIQANIPGAAY SGRETVYPNGSLLFQNITLE DAGSYTLRTINASYDSDQAT GQLHVHQNNVPGLPVGAVAG |
| Tissue Specificity | Granulocytes. |
| Post Translational Modifications | N-glycosylated. The cytoplasmic ITAM-like sequence becomes tyrosine phosphorylated by SRC family PTKs upon ligand-mediated receptor clustering and allows to initiate phagocytosis of bound ligand. |
| Function | Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles. |
| Protein Name | Cell Adhesion Molecule Ceacam4Carcinoembryonic Antigen Cgm7Carcinoembryonic Antigen-Related Cell Adhesion Molecule 4Cea Cell Adhesion Molecule 4Non-Specific Cross-Reacting Antigen W236 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cell Adhesion Molecule Ceacam4 antibodyAnti-Carcinoembryonic Antigen Cgm7 antibodyAnti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 4 antibodyAnti-Cea Cell Adhesion Molecule 4 antibodyAnti-Non-Specific Cross-Reacting Antigen W236 antibodyAnti-CEACAM4 antibodyAnti-CGM7 antibody |
Information sourced from Uniprot.org