| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CDO1 |
| Gene ID: | 1036 |
| Uniprot ID: | CDO1_HUMAN |
| Immunogen Region: | 1-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CDO1 (NP_001792.2). |
| Immunogen Sequence: | MEQTEVLKPRTLADLIRILH QLFAGDEVNVEEVQAIMEAY ESDPTEWAMYAKFDQYRYTR NLVDQGNGKFNLMILCWGEG HGSSIHDHTNSHCFLKMLQG NLKETLFAWPDKKSNEMVKK SERVLRENQCAYINDSIGLH RVENISHTEPAVSLHLYSPP FDTCHAFDQRTGHKNKVTMT FHSKFGIRTPNATSGSLENN |
| Tissue Specificity | Highly expressed in liver and placenta. Low expression in heart, brain and pancreas. Also detected in hepatoblastoma Hep-G2 cells. |
| Post Translational Modifications | The thioether cross-link between Cys-93 and Tyr-157 plays a structural role through stabilizing the Fe(2+) ion, and prevents the production of highly damaging free hydroxyl radicals by holding the oxygen radical via hydroxyl hydrogen. |
| Function | Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen. |
| Protein Name | Cysteine Dioxygenase Type 1Cysteine Dioxygenase Type ICdoCdo-I |
| Database Links | Reactome: R-HSA-1614558 |
| Alternative Antibody Names | Anti-Cysteine Dioxygenase Type 1 antibodyAnti-Cysteine Dioxygenase Type I antibodyAnti-Cdo antibodyAnti-Cdo-I antibodyAnti-CDO1 antibody |
Information sourced from Uniprot.org