Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-CDH17 (23-240) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CDH17 |
Gene ID: |
1015 |
Uniprot ID: |
CAD17_HUMAN |
Immunogen Region: |
23-240 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 23-240 of human LI Cadherin/Cadherin-17 (Q12864). |
Immunogen Sequence: |
QEGKFSGPLKPMTFSIYEGQ EPSQIIFQFKANPPAVTFEL TGETDNIFVIEREGLLYYNR ALDRETRSTHNLQVAALDAN GIIVEGPVPITIKVKDINDN RPTFLQSKYEGSVRQNSRPG KPFLYVNATDLDDPATPNGQ LYYQIVIQLPMINNVMYFQI NNKTGAISLTREGSQELNPA KNPSYNLVISVKDMGGQSEN SFSDTTSVDIIVTENIWK |
Tissue Specificity | Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. |
Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. |
Protein Name | Cadherin-17Intestinal Peptide-Associated Transporter Hpt-1Liver-Intestine CadherinLi-Cadherin |
Database Links | Reactome: R-HSA-418990 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Cadherin-17 antibodyAnti-Intestinal Peptide-Associated Transporter Hpt-1 antibodyAnti-Liver-Intestine Cadherin antibodyAnti-Li-Cadherin antibodyAnti-CDH17 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance