| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CDH17 |
| Gene ID: | 1015 |
| Uniprot ID: | CAD17_HUMAN |
| Immunogen Region: | 23-240 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-240 of human LI Cadherin/Cadherin-17 (Q12864). |
| Immunogen Sequence: | QEGKFSGPLKPMTFSIYEGQ EPSQIIFQFKANPPAVTFEL TGETDNIFVIEREGLLYYNR ALDRETRSTHNLQVAALDAN GIIVEGPVPITIKVKDINDN RPTFLQSKYEGSVRQNSRPG KPFLYVNATDLDDPATPNGQ LYYQIVIQLPMINNVMYFQI NNKTGAISLTREGSQELNPA KNPSYNLVISVKDMGGQSEN SFSDTTSVDIIVTENIWK |
| Tissue Specificity | Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. |
| Protein Name | Cadherin-17Intestinal Peptide-Associated Transporter Hpt-1Liver-Intestine CadherinLi-Cadherin |
| Database Links | Reactome: R-HSA-418990 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cadherin-17 antibodyAnti-Intestinal Peptide-Associated Transporter Hpt-1 antibodyAnti-Liver-Intestine Cadherin antibodyAnti-Li-Cadherin antibodyAnti-CDH17 antibody |
Information sourced from Uniprot.org