| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CDH13 |
| Gene ID: | 1012 |
| Uniprot ID: | CAD13_HUMAN |
| Immunogen Region: | 120-370 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-370 of human Cadherin-13 (Cadherin-13 (CDH13) ) (NP_001248.1). |
| Immunogen Sequence: | SLQDIFKFARTSPVPRQKRS IVVSPILIPENQRQPFPRDV GKVVDSDRPERSKFRLTGKG VDQEPKGIFRINENTGSVSV TRTLDREVIAVYQLFVETTD VNGKTLEGPVPLEVIVIDQN DNRPIFREGPYIGHVMEGSP TGTTVMRMTAFDADDPATDN ALLRYNIRQQTPDKPSPNMF YIDPEKGDIVTVVSPALLDR ETLENPKYELIIEAQDMAGL DVGLTGTATATIMIDDKND |
| Tissue Specificity | Highly expressed in heart. In the CNS, expressed in cerebral cortex, medulla, hippocampus, amygdala, thalamus and substantia nigra. No expression detected in cerebellum or spinal cord. |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth. |
| Protein Name | Cadherin-13Heart CadherinH-CadherinP105Truncated CadherinT-CadT-Cadherin |
| Database Links | Reactome: R-HSA-418990 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorCytoplasm |
| Alternative Antibody Names | Anti-Cadherin-13 antibodyAnti-Heart Cadherin antibodyAnti-H-Cadherin antibodyAnti-P105 antibodyAnti-Truncated Cadherin antibodyAnti-T-Cad antibodyAnti-T-Cadherin antibodyAnti-CDH13 antibodyAnti-CDHH antibody |
Information sourced from Uniprot.org