| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-CD30 is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | Ber‐H2 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1/Kappa |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: | Affinity purified |
| Dilution Range: | 1:100‐200 |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | TNFRSF8 |
| Gene ID: | 943 |
| Uniprot ID: | TNR8_HUMAN |
| Specificity: | Positive control: Hodgkin lymphoma or anaplastic large cell lymphoma |
| Immunogen: | Co cell line established from a patient with Hodgkin's disease of T-cell lineage |
| Tissue Specificity | Isoform 2: Detected in alveolar macrophages (at protein level). |
| Post Translational Modifications | Phosphorylated on serine and tyrosine residues (Probable). Isoform 2 is constitutively phosphorylated. |
| Function | Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 8Cd30l ReceptorKi-1 AntigenLymphocyte Activation Antigen Cd30Cd Antigen Cd30 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 8 antibodyAnti-Cd30l Receptor antibodyAnti-Ki-1 Antigen antibodyAnti-Lymphocyte Activation Antigen Cd30 antibodyAnti-Cd Antigen Cd30 antibodyAnti-TNFRSF8 antibodyAnti-CD30 antibodyAnti-D1S166E antibody |
Information sourced from Uniprot.org