Anti-CD10 antibody [FR4D11] (STJ16101083)

SKU:
STJ16101083

$332.78 - $1,509.98
Current Stock:
Host: Mouse
Applications: FC, IF, IHC
Reactivity: Human
Note: FOR RESEARCH USE ONLY (RUO).
Short Description: Mouse monoclonal antibody anti-CD10 is suitable for use in Flow Cytometry, Immunofluorescence and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: FR4D11
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: PBS with 0.02% Sodium Azide
Purification: Affinity purified from tissue culture.
Concentration: Available as 0.1 mg/mL, 0.5 mg/mL or 1mg/mL. Please check against pricing options.
Dilution Range: Flow cytometry (0.5-1.0 µg/million cells in 0.1 ml). Immunofluorescence (0.5-1.0 µg/ml). Immunohistology (1-2 µg/ml for 30 min at RT; an appropriate antigen retrieval method for staining of formalin-fixed tissues has not been established to date).
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: A BALB/c mice was immunized with Raji cells. NA NA NA NA Fusion partner: X63-Ag8.653. NA NA NA NA
Background FR4D11 reacts with high affinity to CD10 or CALLA, a cell surface enzyme with neutral metalloendopeptidase activity, inactivating a variety of biologically active peptides. CD10 is a 100 kDa glycoprotein, expressed on 70% of pre-B ALL-cells (common ALL) , but also on early lymphoid progenitor-cells in bone marrow and fetal liver. Other normal CD10 positive tissues include renal epithelium, fibroblasts and germinal centre B-cells. Density of CD10 antigen has been shown to be related to cell differentiation and may have prognostic value for B-cell lineage acute leukemia. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance