| Host: |
Rabbit |
| Applications: |
WB/IHC-P/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000IHC-P:1:200-1:800ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
CCR10 |
| Gene ID: |
2826 |
| Uniprot ID: |
CCR10_HUMAN |
| Immunogen Region: |
1-100 aa |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CCR10 (NP_057686.2). |
| Immunogen Sequence: |
MGTEATEQVSWGHYSGDEED AYSAEPLPELCYKADVQAFS RAFQPSVSLTVAALGLAGNG LVLATHLAARRAARSPTSAH LLQLALADLLLALTLPFAAA |
| Tissue Specificity | Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells. |
| Function | Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line. |
| Protein Name | C-C Chemokine Receptor Type 10C-C Ckr-10Cc-Ckr-10Ccr-10G-Protein Coupled Receptor 2 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-C Chemokine Receptor Type 10 antibodyAnti-C-C Ckr-10 antibodyAnti-Cc-Ckr-10 antibodyAnti-Ccr-10 antibodyAnti-G-Protein Coupled Receptor 2 antibodyAnti-CCR10 antibodyAnti-GPR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
