| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Putative caspase recruitment domain-containing protein 17P (22-72 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CARD17P |
| Uniprot ID: | CAR17_HUMAN |
| Immunogen Region: | 22-72 aa |
| Specificity: | This antibody detects endogenous levels of human CAR17 |
| Immunogen: | Synthesized peptide derived from the human CAR17 at the amino acid range 22-72 |
| Function | Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation. |
| Protein Name | Putative Caspase Recruitment Domain-Containing Protein 17pCaspase-1 Inhibitor IncaInhibitory Caspase Recruitment Domain Protein |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Putative Caspase Recruitment Domain-Containing Protein 17p antibodyAnti-Caspase-1 Inhibitor Inca antibodyAnti-Inhibitory Caspase Recruitment Domain Protein antibodyAnti-CARD17P antibodyAnti-CARD17 antibodyAnti-INCA antibody |
Information sourced from Uniprot.org