Host: | Rabbit |
Applications: | IHC/ELISA |
Reactivity: | Human |
Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Putative Caspase Recruitment Domain-Containing Protein 17p is suitable for use in Immunohistochemistry and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification: | Affinity purification |
Concentration: | 0.7 mg/mL |
Dilution Range: | IHC 1:50-1:200 |
Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
Gene Symbol: | CARD17P |
Uniprot ID: | CAR17_HUMAN |
Immunogen: | Synthetic peptide of human CARD17 |
Tissue Specificity | Ubiquitous. |
Function | Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation. |
Protein Name | Putative Caspase Recruitment Domain-Containing Protein 17pCaspase-1 Inhibitor IncaInhibitory Caspase Recruitment Domain Protein |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Putative Caspase Recruitment Domain-Containing Protein 17p antibodyAnti-Caspase-1 Inhibitor Inca antibodyAnti-Inhibitory Caspase Recruitment Domain Protein antibodyAnti-CARD17P antibodyAnti-CARD17 antibodyAnti-INCA antibody |
Information sourced from Uniprot.org