Western blot analysis of extracts of various cell lines, using CADM3 antibody (STJ26947) at 1:2000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-CADM3 antibody (25-330) (STJ26947)

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STJ26947
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CADM3
Gene ID: 57863
Uniprot ID: CADM3_HUMAN
Immunogen Region: 25-330
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 25-330 of human CADM3 (NP_001120645.1).
Immunogen Sequence: NLSQDDSQPWTSDETVVAGG TVVLKCQVKDHEDSSLQWSN PAQQTLYFGEKRALRDNRIQ LVTSTPHELSISISNVALAD EGEYTCSIFTMPVRTAKSLV TVLGIPQKPIITGYKSSLRE KDTATLNCQSSGSKPAARLT WRKGDQELHGEPTRIQEDPN GKTFTVSSSVTFQVTREDDG ASIVCSVNHESLKGADRSTS QRIEVLYTPTAMIRPDPPHP REGQKLLLHCEGRGNPVPQ
Tissue Specificity Isoform 1 is expressed mainly in adult and fetal brain. Isoform 2 is highly expressed in adult brain and weakly expressed in placenta. In brain, Isoform 2 is highly expressed in cerebellum.
Function Involved in cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions.
Protein Name Cell Adhesion Molecule 3
Brain Immunoglobulin Receptor
Immunoglobulin Superfamily Member 4b
Igsf4b
Nectin-Like Protein 1
Necl-1
Synaptic Cell Adhesion Molecule 3
Syncam3
Tslc1-Like Protein 1
Tsll1
Database Links Reactome: R-HSA-418990
Reactome: R-HSA-420597
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Alternative Antibody Names Anti-Cell Adhesion Molecule 3 antibody
Anti-Brain Immunoglobulin Receptor antibody
Anti-Immunoglobulin Superfamily Member 4b antibody
Anti-Igsf4b antibody
Anti-Nectin-Like Protein 1 antibody
Anti-Necl-1 antibody
Anti-Synaptic Cell Adhesion Molecule 3 antibody
Anti-Syncam3 antibody
Anti-Tslc1-Like Protein 1 antibody
Anti-Tsll1 antibody
Anti-CADM3 antibody
Anti-IGSF4B antibody
Anti-NECL1 antibody
Anti-SYNCAM3 antibody
Anti-TSLL1 antibody
Anti-UNQ225 antibody
Anti-PRO258 antibody

Information sourced from Uniprot.org

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