Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-BRD1 (1-250) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
BRD1 |
Gene ID: |
23774 |
Uniprot ID: |
BRD1_HUMAN |
Immunogen Region: |
1-250 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human BRD1 (NP_055392.1). |
Immunogen Sequence: |
MRRKGRCHRGSAARHPSSPC SVKHSPTRETLTYAQAQRMV EIEIEGRLHRISIFDPLEII LEDDLTAQEMSECNSNKENS ERPPVCLRTKRHKNNRVKKK NEALPSAHGTPASASALPEP KVRIVEYSPPSAPRRPPVYY KFIEKSAEELDNEVEYDMDE EDYAWLEIVNEKRKGDCVPA VSQSMFEFLMDRFEKESHCE NQKQGEQQSLIDEDAVCCIC MDGECQNSNVILFCDMCNL |
Tissue Specificity | Highly expressed in testis. |
Function | Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, that acts as a regulator of hematopoiesis. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac), thereby promoting erythroid differentiation. |
Protein Name | Bromodomain-Containing Protein 1Br140-Like ProteinBromodomain And Phd Finger-Containing Protein 2 |
Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-6804758 |
Cellular Localisation | NucleusChromosomeLocalizes To Transcription Start Sites |
Alternative Antibody Names | Anti-Bromodomain-Containing Protein 1 antibodyAnti-Br140-Like Protein antibodyAnti-Bromodomain And Phd Finger-Containing Protein 2 antibodyAnti-BRD1 antibodyAnti-BRL antibodyAnti-BRPF2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance