| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BRD1 |
| Gene ID: | 23774 |
| Uniprot ID: | BRD1_HUMAN |
| Immunogen Region: | 1-250 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human BRD1 (NP_055392.1). |
| Immunogen Sequence: | MRRKGRCHRGSAARHPSSPC SVKHSPTRETLTYAQAQRMV EIEIEGRLHRISIFDPLEII LEDDLTAQEMSECNSNKENS ERPPVCLRTKRHKNNRVKKK NEALPSAHGTPASASALPEP KVRIVEYSPPSAPRRPPVYY KFIEKSAEELDNEVEYDMDE EDYAWLEIVNEKRKGDCVPA VSQSMFEFLMDRFEKESHCE NQKQGEQQSLIDEDAVCCIC MDGECQNSNVILFCDMCNL |
| Tissue Specificity | Highly expressed in testis. |
| Function | Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, that acts as a regulator of hematopoiesis. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac), thereby promoting erythroid differentiation. |
| Protein Name | Bromodomain-Containing Protein 1Br140-Like ProteinBromodomain And Phd Finger-Containing Protein 2 |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-6804758 |
| Cellular Localisation | NucleusChromosomeLocalizes To Transcription Start Sites |
| Alternative Antibody Names | Anti-Bromodomain-Containing Protein 1 antibodyAnti-Br140-Like Protein antibodyAnti-Bromodomain And Phd Finger-Containing Protein 2 antibodyAnti-BRD1 antibodyAnti-BRL antibodyAnti-BRPF2 antibody |
Information sourced from Uniprot.org