| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BFSP2 |
| Gene ID: | 8419 |
| Uniprot ID: | BFSP2_HUMAN |
| Immunogen Region: | 116-415 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 116-415 of human BFSP2 (NP_003562.1). |
| Immunogen Sequence: | VEYMAKVHALEQVSQELETQ LRMHLESKATRSGNWGALRA SWASSCQQVGEAVLENARLM LQTETIQAGADDFKERYENE QPFRKAAEEEINSLYKVIDE ANLTKMDLESQIESLKEELG SLSRNYEEDVKLLHKQLAGC ELEQMDAPIGTGLDDILETI RIQWERDVEKNRVEAGALLQ AKQQAEVAHMSQTQEEKLAA ALRVELHNTSCQVQSLQAET ESLRALKRGLENTLHDAKH |
| Tissue Specificity | Lens. |
| Function | Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA. Plays a role in maintenance of retinal lens optical clarity. |
| Protein Name | Phakinin49 Kda Cytoskeletal ProteinBeaded Filament Structural Protein 2Lens Fiber Cell Beaded Filament Protein Cp 47Cp47Lens Fiber Cell Beaded Filament Protein Cp 49Cp49Lens Intermediate Filament-Like LightLifl-L |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonCell CortexExpressed Primarily At The Plasma Membrane In Peripheral Lens Fiber CellsHowever Also Localizes To The Cytoplasm In Mature Lens Fiber Cells |
| Alternative Antibody Names | Anti-Phakinin antibodyAnti-49 Kda Cytoskeletal Protein antibodyAnti-Beaded Filament Structural Protein 2 antibodyAnti-Lens Fiber Cell Beaded Filament Protein Cp 47 antibodyAnti-Cp47 antibodyAnti-Lens Fiber Cell Beaded Filament Protein Cp 49 antibodyAnti-Cp49 antibodyAnti-Lens Intermediate Filament-Like Light antibodyAnti-Lifl-L antibodyAnti-BFSP2 antibody |
Information sourced from Uniprot.org