Anti-Bcl-6 Oncoprotein antibody [LN22] (STJ16101682)

Anti-Bcl-6 Oncoprotein antibody [LN22] (STJ16101682)

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STJ16101682-1
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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-Bcl-6 Oncoprotein is suitable for use in Immunohistochemistry research applications.
Clonality : Monoclonal
Clone ID : LN22
Conjugation: Unconjugated
Isotype: IgG2b
Formulation: Tissue culture supernatant with sodium azide
Concentration: >=220 mg/L
Dilution Range: IHC-P 1:60
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Prokaryotic recombinant protein containing 1–350 amino acids of the N-terminus of the Bcl-6 human oncoprotein molecule.
Background Bcl-6 is a proto-oncogene that encodes a Kruppel-type zinc-finger protein of 95 kD and shares homology with other transcription factors. Bcl-6 protein is mainly expressed in normal germinal center B cells and related lymphomas. It has been shown that the Bcl-6 proto-oncogene is involved in chromosome rearrangements at 3q27 in non-Hodgkin s lymphomas and Bcl-6 rearrangements have also been detected in 33-45% of diffuse large B cell lymphomas. Immunohistochemistry has been reported to show the Bcl-6 gene product to be detectable in follicular lymphomas, diffuse large B cell lymphomas, Burkitt s lymphomas and in nodular, lymphocyte predominant Hodgkin s disease.

Information sourced from Uniprot.org

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