![Anti-Bcl-6 Oncoprotein antibody [LN22] (STJ16101682)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/152188/347040/STJ16101682_1__28412.1681999296.jpg?c=1 "Anti-Bcl-6 Oncoprotein antibody [LN22] (STJ16101682)")
![Anti-Bcl-6 Oncoprotein antibody [LN22] (STJ16101682)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/152188/347040/STJ16101682_1__28412.1681999296.jpg?c=1 "Anti-Bcl-6 Oncoprotein antibody [LN22] (STJ16101682)")
| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Bcl-6 Oncoprotein is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | LN22 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Formulation: | Tissue culture supernatant with sodium azide |
| Concentration: | >=220 mg/L |
| Dilution Range: | IHC-P 1:60 |
| Storage Instruction: | Store at 2-8°C upon receipt. |
| Immunogen: | Prokaryotic recombinant protein containing 1–350 amino acids of the N-terminus of the Bcl-6 human oncoprotein molecule. |
| Background | Bcl-6 is a proto-oncogene that encodes a Kruppel-type zinc-finger protein of 95 kD and shares homology with other transcription factors. Bcl-6 protein is mainly expressed in normal germinal center B cells and related lymphomas. It has been shown that the Bcl-6 proto-oncogene is involved in chromosome rearrangements at 3q27 in non-Hodgkin s lymphomas and Bcl-6 rearrangements have also been detected in 33-45% of diffuse large B cell lymphomas. Immunohistochemistry has been reported to show the Bcl-6 gene product to be detectable in follicular lymphomas, diffuse large B cell lymphomas, Burkitt s lymphomas and in nodular, lymphocyte predominant Hodgkin s disease. |
Information sourced from Uniprot.org
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