Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-ATP11B (1-60) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ATP11B |
Gene ID: |
23200 |
Uniprot ID: |
AT11B_HUMAN |
Immunogen Region: |
1-60 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human ATP11B (NP_055431.1). |
Immunogen Sequence: |
MWRWIRQQLGFDPPHQSDTR TIYVANRFPQNGLYTPQKFI DNRIISSKYTVWNFVPKNLF |
Function | Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of intracellular membranes. May contribute to the maintenance of membrane lipid asymmetry in endosome compartment. |
Protein Name | Phospholipid-Transporting Atpase IfAtpase IrAtpase Class Vi Type 11bP4-Atpase Flippase Complex Alpha Subunit Atp11b |
Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-936837 |
Cellular Localisation | Recycling Endosome MembraneMulti-Pass Membrane ProteinEarly EndosomeEndoplasmic ReticulumGolgi ApparatusTrans-Golgi NetworkExit From The Endoplasmic Reticulum Requires The Presence Of Tmem30aBut Not Tmem30bIn The Presence Of Tmem30aMainly Located In Recycling Endosomes |
Alternative Antibody Names | Anti-Phospholipid-Transporting Atpase If antibodyAnti-Atpase Ir antibodyAnti-Atpase Class Vi Type 11b antibodyAnti-P4-Atpase Flippase Complex Alpha Subunit Atp11b antibodyAnti-ATP11B antibodyAnti-ATPIF antibodyAnti-ATPIR antibodyAnti-KIAA0956 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance