| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AS3MT |
| Gene ID: | 57412 |
| Uniprot ID: | AS3MT_HUMAN |
| Immunogen Region: | 216-375 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 216-375 of human AS3MT (NP_065733.2). |
| Immunogen Sequence: | LAVLAQKIGFCPPRLVTANL ITIQNKELERVIGDCRFVSA TFRLFKHSKTGPTKRCQVIY NGGITGHEKELMFDANFTFK EGEIVEVDEETAAILKNSRF AQDFLIRPIGEKLPTSGGCS ALELKDIITDPFKLAEESDS MKSRCVPDAAGGCCGTKKSC |
| Function | Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH. |
| Protein Name | Arsenite MethyltransferaseMethylarsonite MethyltransferaseS-Adenosyl-L-Methionine -Arsenic(Iii Methyltransferase |
| Database Links | Reactome: R-HSA-156581 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Arsenite Methyltransferase antibodyAnti-Methylarsonite Methyltransferase antibodyAnti-S-Adenosyl-L-Methionine -Arsenic(Iii Methyltransferase antibodyAnti-AS3MT antibodyAnti-CYT19 antibody |
Information sourced from Uniprot.org