Anti-ARPC1B antibody (10-80 aa) (STJ11106282)

SKU:
STJ11106282
$151.88 - $708.08
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: ARPC1B
Gene ID: 10095
Uniprot ID: ARC1B_HUMAN
Immunogen Region: 10-80 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 10-80 of human ARPC1B (NP_005711.1).
Immunogen Sequence: PISCHAWNKDRTQIAICPNN HEVHIYEKSGAKWTKVHELK EHNGQVTGIDWAPESNRIVT CGTDRNAYVWT
Function Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
Protein Name Actin-Related Protein 2/3 Complex Subunit 1b
Arp2/3 Complex 41 Kda Subunit
P41-Arc
Database Links Reactome: R-HSA-2029482
Reactome: R-HSA-3928662
Reactome: R-HSA-5663213
Reactome: R-HSA-9664422
Cellular Localisation Cytoplasm
Cytoskeleton
Nucleus
Alternative Antibody Names Anti-Actin-Related Protein 2/3 Complex Subunit 1b antibody
Anti-Arp2/3 Complex 41 Kda Subunit antibody
Anti-P41-Arc antibody
Anti-ARPC1B antibody
Anti-ARC41 antibody

Information sourced from Uniprot.org

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