| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ARL2BP (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ARL2BP |
| Gene ID: |
23568 |
| Uniprot ID: |
AR2BP_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ARL2BP (NP_036238.1). |
| Immunogen Sequence: |
MDALEGESFALSFSSASDAE FDAVVGYLEDIIMDDEFQLL QRNFMDKYYLEFEDTEENKL IYTPIFNEYISLVEKYIEEQ LLQRIPEFNMAAFTTTLQHH |
| Tissue Specificity | Expressed in retina pigment epithelial cells (at protein level). Widely expressed. |
| Function | Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2. |
| Protein Name | Adp-Ribosylation Factor-Like Protein 2-Binding ProteinArf-Like 2-Binding ProteinArl2-Binding ProteinBinder Of Arf2 Protein 1 |
| Database Links | Reactome: R-HSA-83936 |
| Cellular Localisation | CytoplasmMitochondrion Intermembrane SpaceCytoskeletonMicrotubule Organizing CenterCentrosomeNucleusSpindleCilium Basal BodyThe Complex Formed With Arl2bpArl2 And Slc25a4 Is Expressed In MitochondriaDetected In The Midbody MatrixNot Detected In The GolgiNucleus And On The Mitotic SpindleCentrosome-Associated Throughout The Cell CycleNot Detected To Interphase MicrotubulesIn Retina Photoreceptor CellsLocalized In The Distal Connecting CiliaBasal BodyCiliary-Associated CentrioleAnd Ciliary RootletInteraction With Arl2 May Be Required For Cilia Basal Body Localization |
| Alternative Antibody Names | Anti-Adp-Ribosylation Factor-Like Protein 2-Binding Protein antibodyAnti-Arf-Like 2-Binding Protein antibodyAnti-Arl2-Binding Protein antibodyAnti-Binder Of Arf2 Protein 1 antibodyAnti-ARL2BP antibodyAnti-BART antibodyAnti-BART1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
