| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARAP2 |
| Gene ID: | 116984 |
| Uniprot ID: | ARAP2_HUMAN |
| Immunogen Region: | 1405-1704 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1405-1704 of human ARAP2 (NP_056045.2). |
| Immunogen Sequence: | LAEPGSAYLVVKRFLTADTI KHCSDRSTLGSIKEGILKIK EEPSKILSGNKFQDRYFVLR DGFLFLYKDVKSSKHDKMFS LSSMKFYRGVKKKMKPPTSW GLTAYSEKHHWHLCCDSSRT QTEWMTSIFIAQHEYDIWPP AGKERKRSITKNPKIGGLPL IPIQHEGNATLARKNIESAR AELERLRLSEKCDKESVDSS LKERASMVAHCLEHKDDKLR NRPRKHRSFNCLEDTEPEA |
| Tissue Specificity | Detected in brain, thymus, lymph node, thyroid, spinal cord, trachea, heart, skeletal muscle, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. |
| Function | Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. |
| Protein Name | Arf-Gap With Rho-Gap Domain - Ank Repeat And Ph Domain-Containing Protein 2 Centaurin-Delta-1 Cnt-D1 Protein Parx |
| Database Links | Reactome: R-HSA-8980692 Reactome: R-HSA-9013148 Reactome: R-HSA-9013149 Reactome: R-HSA-9013423 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Arf-Gap With Rho-Gap Domain - Ank Repeat And Ph Domain-Containing Protein 2 antibody Anti-Centaurin-Delta-1 antibody Anti-Cnt-D1 antibody Anti-Protein Parx antibody Anti-ARAP2 antibody Anti-CENTD1 antibody Anti-KIAA0580 antibody |
Information sourced from Uniprot.org