| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ANGPT4 |
| Gene ID: | 51378 |
| Uniprot ID: | ANGP4_HUMAN |
| Immunogen Region: | 25-260 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-260 of human ANGPT4 (NP_057069.1). |
| Immunogen Sequence: | TRQEADRGCETLVVQHGHCS YTFLLPKSEPCPPGPEVSRD SNTLQRESLANPLHLGKLPT QQVKQLEQALQNNTQWLKKL ERAIKTILRSKLEQVQQQMA QNQTAPMLELGTSLLNQTTA QIRKLTDMEAQLLNQTSRMD AQMPETFLSTNKLENQLLLQ RQKLQQLQGQNSALEKRLQA LETKQQEELASILSKKAKLL NTLSRQSAALTNIERGLRGV RHNSSLLQDQQHSLRQ |
| Tissue Specificity | Highly expressed in the lung with much lower levels found in other tissues. |
| Function | Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis. |
| Protein Name | Angiopoietin-4Ang-4Angiopoietin-3Ang-3 |
| Database Links | Reactome: R-HSA-210993 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Angiopoietin-4 antibodyAnti-Ang-4 antibodyAnti-Angiopoietin-3 antibodyAnti-Ang-3 antibodyAnti-ANGPT4 antibodyAnti-ANG3 antibodyAnti-ANG4 antibody |
Information sourced from Uniprot.org