Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-ANAPC13 (1-74) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ANAPC13 |
Gene ID: |
25847 |
Uniprot ID: |
APC13_HUMAN |
Immunogen Region: |
1-74 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-74 of human ANAPC13 (NP_056206.1). |
Immunogen Sequence: |
MDSEVQRDGRILDLIDDAWR EDKLPYEDVAIPLNELPEPE QDNGGTTESVKEQEMKWTDL ALQYLHENVPPIGN |
Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. |
Protein Name | Anaphase-Promoting Complex Subunit 13Apc13Cyclosome Subunit 13 |
Database Links | Reactome: R-HSA-983168 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Anaphase-Promoting Complex Subunit 13 antibodyAnti-Apc13 antibodyAnti-Cyclosome Subunit 13 antibodyAnti-ANAPC13 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance