Anti-ANAPC13 antibody (1-74) (STJ112008)

SKU:
STJ112008

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ANAPC13 (1-74) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ANAPC13
Gene ID: 25847
Uniprot ID: APC13_HUMAN
Immunogen Region: 1-74
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-74 of human ANAPC13 (NP_056206.1).
Immunogen Sequence: MDSEVQRDGRILDLIDDAWR EDKLPYEDVAIPLNELPEPE QDNGGTTESVKEQEMKWTDL ALQYLHENVPPIGN
Function Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Protein Name Anaphase-Promoting Complex Subunit 13
Apc13
Cyclosome Subunit 13
Database Links Reactome: R-HSA-983168
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Anaphase-Promoting Complex Subunit 13 antibody
Anti-Apc13 antibody
Anti-Cyclosome Subunit 13 antibody
Anti-ANAPC13 antibody

Information sourced from Uniprot.org

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