| Tissue Specificity | Isoform 1 is detected in thymus, prostate, testis, ovary, colon and small intestine. Isoform 2 is highly expressed in testis and detected at much lower levels in kidney, pancreas, liver, lung and brain. |
| Function | Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane. Involved in mitochondrial-mediated antiviral innate immunity. Promotes translocation of NDUFS1 into mitochondria to regulate mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) activity. |
| Protein Name | A-Kinase Anchor Protein 1 - MitochondrialA-Kinase Anchor Protein 149 KdaAkap 149Dual Specificity A-Kinase-Anchoring Protein 1D-Akap-1Protein Kinase A-Anchoring Protein 1Prka1Spermatid A-Kinase Anchor Protein 84S-Akap84 |
| Database Links | Reactome: R-HSA-8949215Reactome: R-HSA-983231 |
| Cellular Localisation | Mitochondrion Outer MembraneMitochondrion |
| Alternative Antibody Names | Anti-A-Kinase Anchor Protein 1 - Mitochondrial antibodyAnti-A-Kinase Anchor Protein 149 Kda antibodyAnti-Akap 149 antibodyAnti-Dual Specificity A-Kinase-Anchoring Protein 1 antibodyAnti-D-Akap-1 antibodyAnti-Protein Kinase A-Anchoring Protein 1 antibodyAnti-Prka1 antibodyAnti-Spermatid A-Kinase Anchor Protein 84 antibodyAnti-S-Akap84 antibodyAnti-AKAP1 antibodyAnti-AKAP149 antibodyAnti-PRKA1 antibody |
Information sourced from Uniprot.org
