| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AIFM3 |
| Gene ID: | 150209 |
| Uniprot ID: | AIFM3_HUMAN |
| Immunogen Region: | 1-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human AIFM3 (NP_001018070.1). |
| Immunogen Sequence: | MGGCFSKPKPVELKIEVVLP EKERGKEELSASGKGSPRAY QGNGTARHFHTEERLSTPHP YPSPQDCVEAAVCHVKDLEN GQMREVELGWGKVLLVKDNG EFHALGHKCPHYGAPLVKGV LSRGRVRCPWHGACFNISTG DLEDFPGLDSLHKFQVKIEK EKVYVRASKQALQLQRRTKV MAKCISPSAGYSSSTNVLIV |
| Tissue Specificity | Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level). |
| Function | Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential. |
| Protein Name | Apoptosis-Inducing Factor 3Apoptosis-Inducing Factor-Like Protein |
| Cellular Localisation | MitochondrionDoes Not Translocate To The Nucleus Upon Induction Of Apoptosis |
| Alternative Antibody Names | Anti-Apoptosis-Inducing Factor 3 antibodyAnti-Apoptosis-Inducing Factor-Like Protein antibodyAnti-AIFM3 antibodyAnti-AIFL antibody |
Information sourced from Uniprot.org