| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AGL |
| Gene ID: |
178 |
| Uniprot ID: |
GDE_HUMAN |
| Immunogen Region: |
1233-1532 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1233-1532 of human AGL (NP_000633.2). |
| Immunogen Sequence: |
EGFNITAGVDEETGFVYGGN RFNCGTWMDKMGESDRARNR GIPATPRDGSAVEIVGLSKS AVRWLLELSKKNIFPYHEVT VKRHGKAIKVSYDEWNRKIQ DNFEKLFHVSEDPSDLNEKH PNLVHKRGIYKDSYGASSPW CDYQLRPNFTIAMVVAPELF TTEKAWKALEIAEKKLLGPL GMKTLDPDDMVYCGIYDNAL DNDNYNLAKGFNYHQGPEWL WPIGYFLRAKLYFSRLMGP |
| Tissue Specificity | Liver, kidney and lymphoblastoid cells express predominantly isoform 1.whereas muscle and heart express not only isoform 1, but also muscle-specific isoform mRNAs (isoforms 2, 3 and 4). Isoforms 5 and 6 are present in both liver and muscle. |
| Post Translational Modifications | The N-terminus is blocked. Ubiquitinated. |
| Function | Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation. |
| Protein Name | Glycogen Debranching EnzymeGlycogen Debrancher Includes - 4-Alpha-GlucanotransferaseOligo-1 -4-1 -4-Glucantransferase - Amylo-Alpha-1 -6-GlucosidaseAmylo-1 -6-GlucosidaseDextrin 6-Alpha-D-Glucosidase |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-70221 |
| Cellular Localisation | CytoplasmUnder Glycogenolytic Conditions Localizes To The Nucleus |
| Alternative Antibody Names | Anti-Glycogen Debranching Enzyme antibodyAnti-Glycogen Debrancher Includes - 4-Alpha-Glucanotransferase antibodyAnti-Oligo-1 -4-1 -4-Glucantransferase - Amylo-Alpha-1 -6-Glucosidase antibodyAnti-Amylo-1 -6-Glucosidase antibodyAnti-Dextrin 6-Alpha-D-Glucosidase antibodyAnti-AGL antibodyAnti-GDE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
