| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AFMID (1-303) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AFMID |
| Gene ID: |
125061 |
| Uniprot ID: |
KFA_HUMAN |
| Immunogen Region: |
1-303 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human AFMID (NP_001010982.2). |
| Immunogen Sequence: |
MMDVSGVGFPSKVPWKKMSA EELENQYCPSRWVVRLGAEE ALRTYSQIGIEATTRARATR KSLLHVPYGDGEGEKVDIYF PDESSEALPFFLFFHGGYWQ SGSKDESAFMVHPLTAQGVA VVIVAYGIAPKGTLDHMVDQ VTRSVAFVQKRYPSNKGIYL CGHSAGAHLAAMMLLADWTK HGVTPNLRGFFLVSGVFDLE PIVYTSQNVALQLTLEDAQR NSPQLKVAQAQPVDPTCRV |
| Function | Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. |
| Protein Name | Kynurenine FormamidaseKfaKfaseArylformamidaseN-Formylkynurenine FormamidaseFkf |
| Database Links | Reactome: R-HSA-71240 |
| Cellular Localisation | CytoplasmCytosolNucleusPredominantly CytosolicSome Fraction Is Nuclear |
| Alternative Antibody Names | Anti-Kynurenine Formamidase antibodyAnti-Kfa antibodyAnti-Kfase antibodyAnti-Arylformamidase antibodyAnti-N-Formylkynurenine Formamidase antibodyAnti-Fkf antibodyAnti-AFMID antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
