| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AFMID |
| Gene ID: | 125061 |
| Uniprot ID: | KFA_HUMAN |
| Immunogen Region: | 1-303 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human AFMID (NP_001010982.2). |
| Immunogen Sequence: | MMDVSGVGFPSKVPWKKMSA EELENQYCPSRWVVRLGAEE ALRTYSQIGIEATTRARATR KSLLHVPYGDGEGEKVDIYF PDESSEALPFFLFFHGGYWQ SGSKDESAFMVHPLTAQGVA VVIVAYGIAPKGTLDHMVDQ VTRSVAFVQKRYPSNKGIYL CGHSAGAHLAAMMLLADWTK HGVTPNLRGFFLVSGVFDLE PIVYTSQNVALQLTLEDAQR NSPQLKVAQAQPVDPTCRV |
| Function | Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. |
| Protein Name | Kynurenine FormamidaseKfaKfaseArylformamidaseN-Formylkynurenine FormamidaseFkf |
| Database Links | Reactome: R-HSA-71240 |
| Cellular Localisation | CytoplasmCytosolNucleusPredominantly CytosolicSome Fraction Is Nuclear |
| Alternative Antibody Names | Anti-Kynurenine Formamidase antibodyAnti-Kfa antibodyAnti-Kfase antibodyAnti-Arylformamidase antibodyAnti-N-Formylkynurenine Formamidase antibodyAnti-Fkf antibodyAnti-AFMID antibody |
Information sourced from Uniprot.org